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Ad Astra Per Aspera | To the Stars through Difficulties

Ad Astra Per Aspera | To the Stars through Difficulties

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Ovarian Hyperstimulation Syndrome

Ovarian Hyperstimulation Syndrome Overview

Ovarian hyperstimulation can occur as a result of receiving injectable fertility drugs. It can occur in up to 5% of cases, particularly if the patient has polycystic ovary syndrome. In OHSS, there is excessive ovarian enlargement due to an excessive number of growing follicles turned on at the same time. Bloating and a cramping sensation are common. The severe form is accompanied by excessive amounts of fluids leaking into the abdominal and thoracic cavity, leading to a decrease in blood volume, an increase in blood concentration, and thus, an increased risk of clot formation. There is also a risk of renal impairment and a decline in kidney function. In OHS, there is a concomitant increase in abdominal fluid distension (ascites) and increasing difficulty breathing.

The condition cannot occur without receiving the ovulation triggers.eOvidrel or HCG. The early-onset form occurs a few days after the ovulation trigger. The delayed onset form occurs after implantation is established and is due to a gradual rise in the pregnancy hormone HCG. The severity of the symptoms is unpredictable, but generally speaking, the condition is self-limited, and treatment is supportive, ensuring good hydration, controlling discomfort, combating nausea, and occasionally drainage of excessive abdominal and thoracic cavity fluid.

The severity of the symptoms is unpredictable, but generally speaking, the condition is self-limited and treatment is supportive, ensuring good hydration, controlling discomfort, combating nausea, and occasionally drainage of excessive abdominal and thoracic fluid.

Instructions for Patients at Risk of Ovarian Hyperstimulation Syndrome

These instructions are meant to monitor and identify the condition, permitting early therapeutic intervention to minimize the symptoms and eliminate potential risks.

Once you are identified as a potential risk for OHSS, you will be asked to maintain an OHSS chart on a daily basis, recording your weight, abdominal girth, fluid intake and urine output, in addition to recording other symptoms like abdominal pain, nausea, and shortness of breath.

Connect with your nurse on a daily basis to go over your OHSS chart data.

You may be started on medication to combat nausea, control pain and prevent blood clotting. Good hydration with proper fluid intake is a must.

Occasionally, you may need IV fluid administration and abdominal fluid drainage if your abdominal distension is severe enough to cause symptoms. Drainage of fluid may need to be repeated in some cases.

The condition usually resolves within a week. Staying off work is advised during the acute phase of the condition.

Hospital admission is sometimes required in severe cases requiring frequent close monitoring and fluid drainage from the thoracic cavity.